Hydrazine → HCID 67259880、化合物
反応式
[Br:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N+:11]([O-:13])=[O:12])[N:4]([CH2:14][C:15]([O:17]CC)=O)[N:3]=1.[NH2:20][NH2:21]>CCO>[Br:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N+:11]([O-:13])=[O:12])[N:4]([CH2:14][C:15]([NH:20][NH2:21])=[O:17])[N:3]=1参加物
4
実験手順
A solution of ethyl 2-(3-bromo-4-nitro-1H-indazol-1-yl)acetate (1.48 g, 4.51 mmol) in absolute EtOH (20 mL) was treated at ambient temperature with hydrazine (1.45 g, 45.1 mmol) and was heated at reflux for 16 hours under a nitrogen atmosphere. The reaction mixture was cooled to ambient temperature, and the precipitate was isolated by filtration. The solids were dried under vacuum to afford the product (0.865 g) as a tan powder.
後処理
- temperaturewas heated
- temperatureat reflux for 16 hours under a nitrogen atmosphere
- customthe precipitate was isolated by filtration
- customThe solids were dried under vacuum
出典と根拠
- ORDレコード
- ord-bf8e3b566e07458aba1ab44cd33fab30
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08841455B2
反応ノート
読み込み中…