2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one → 4-aminomethyl-6-(2,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-one

HRID 7972

反応式

HRID 7972 の反応式
C(C1C(=O)NN=C(C2C=CC(F)=CC=2F)C=1)(O)=O.[CH2:19]([N:23]1[C:28](=[O:29])[C:27]([CH2:30][N:31]2C(=O)C3=CC=CC=C3C2=O)=[CH:26][C:25]([C:42]2[CH:47]=[CH:46][C:45]([F:48])=[CH:44][C:43]=2[F:49])=[N:24]1)[CH:20]([CH3:22])[CH3:21]>>[NH2:31][CH2:30][C:27]1[C:28](=[O:29])[N:23]([CH2:19][CH:20]([CH3:21])[CH3:22])[N:24]=[C:25]([C:42]2[CH:47]=[CH:46][C:45]([F:48])=[CH:44][C:43]=2[F:49])[CH:26]=1

参加物

3

反応物 2

HCID 219915872-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-oneHCID 219916774-carboxy-6-(2,4-difluorophenyl)-2H-pyridazin-3-one

生成物 1

HCID 219915224-aminomethyl-6-(2,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-one

実験手順

Following the procedure of Example 24 (2), 2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one was reacted to yield the title compound as a slightly yellow oil (yield: 98.4%).

後処理

  1. customwas reacted

出典と根拠

ORDレコード
ord-1fcb1e8a1161461b9c33d7d322bdcc0b
出典データセット
uspto-grants-2006_08
特許番号
US07087606B2

関連ノート

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