Acetic Acid → 1-Methoxycarbonyl-2-isopropylidene hydrazine

HRID 79865

反応式

HRID 79865 の反応式
[CH3:1][O:2][C:3]([NH:5][NH2:6])=[O:4].C(O)(=O)C.O.[CH3:12][C:13]([CH3:15])=O>>[CH3:1][O:2][C:3]([NH:5][N:6]=[C:13]([CH3:15])[CH3:12])=[O:4]

参加物

5

反応物 4

HCID 176Acetic AcidHCID 180AcetoneHCID 962WaterHCID 80519Methyl carbazate

生成物 1

HCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine収率 89%

実験手順

Hydrazinecarboxylic acid methyl ester (5.01 g) were dissolved in acetone (28 mL), and acetic acid (0.0636 mL) was added. The reaction mixture was stirred at room temperature for 24 hours. Water (50 mL) was added, and mixture was extracted three times with DCM (50 mL) and evaporated under vacuum, giving N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g, 89%).

後処理

  1. extractionmixture was extracted three times with DCM (50 mL)
  2. customevaporated under vacuum

出典と根拠

ORDレコード
ord-d0f21b28363a4a90a006665835618b39
出典データセット
uspto-grants-2014_09
特許番号
US08841278B2

関連ノート

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