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HRID 7988作成日:2026年10月25日

2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one → 2-(4-chlorocinnamyl)-6-(4-fluoro-3-methylphenyl)-4-hydroxymethyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/7988

反応式

関与物質

役割名称HCID仕込み量
反応物2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-oneHCID 21991587—
反応物4-carboxy-2-(4-chlorocinnamyl)-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-oneHCID 67213180—
生成物2-(4-chlorocinnamyl)-6-(4-fluoro-3-methylphenyl)-4-hydroxymethyl-2H-pyridazin-3-oneHCID 67213577—

反応手順

Following the procedure of Example 1 (8), 4-carboxy-2-(4-chlorocinnamyl)-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one was reacted to yield the title compound as slightly yellow needles (yield: 17.2%).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07087606B2
出典データセットuspto-grants-2006_08
ORD IDord-f3e9efc20bd94e9a93ba445badfcb9d1
出典メモuspto-grants-2006_08