Potassium Cation → 2-{5-[4-(5-Bromo-thiophen-2-yl)-phenyl]-1H-imidazol-2-yl}-pyrrolidine-1-carboxylic acid tert-butyl ester

反応式

[Br:1][c:2]1[s:3][c:4]([Br:7])[cH:5][cH:6]1.[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH:16]([c:20]2[nH:21][c:22](-[c:25]3[cH:26][cH:27][c:28]([B:31]4[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]4)[cH:29][cH:30]3)[cH:23][n:24]2)[CH2:17][CH2:18][CH2:19]1.[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[K+:40].[K+:41].[O-:42][C:43]([O-:44])=[O:45].[cH:52]1[cH:53][cH:54][c:55]([P:56]([Pd:57]([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[P:96]([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[cH:127][cH:128]1>>[Br:1][c:2]1[s:3][c:4](-[c:28]2[cH:27][cH:26][c:25](-[c:22]3[nH:21][c:20]([CH:16]4[N:15]([C:13]([O:12][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:14])[CH2:19][CH2:18][CH2:17]4)[n:24][cH:23]3)[cH:30][cH:29]2)[cH:5][cH:6]1