1-(4-Fluoro-benzoyl)-3-iodomethyl-pyrrolidine-3-carboxylic acid ethyl ester → 3-[4-(5-Chloro-pyridin-2-yl)-phenoxymethyl]-1-(4-fluoro-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester

HRID 800311

反応式

[CH2:15]([CH3:16])[O:17][C:18](=[O:19])[C:20]1([CH2:34][I:35])[CH2:21][N:22]([C:25]([c:26]2[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]2)=[O:33])[CH2:23][CH2:24]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([OH:14])[cH:12][cH:13]2)[n:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([O:14][CH2:34][C:20]3([C:18]([O:17][CH2:15][CH3:16])=[O:19])[CH2:21][N:22]([C:25]([c:26]4[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]4)=[O:33])[CH2:23][CH2:24]3)[cH:12][cH:13]2)[n:6][cH:7]1