Tert-butyl 2-[(4-methoxypyrrolidin-3-yl)amino]acetate → Ethyl 7-[3-methoxy-4-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]pyrrolidin-1-yl]-4-oxo-1-(1,3-thiazol-2-yl)-1,8-naphthyridine-3-carboxylate

反応式

[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28](=[O:29])[CH2:30][NH:31][CH:32]1[CH2:33][NH:34][CH2:35][CH:36]1[O:37][CH3:38].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8](-[c:18]2[s:19][cH:20][cH:21][n:22]2)[c:9]2[n:10][c:11]([Cl:17])[cH:12][cH:13][c:14]2[c:15]1=[O:16]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8](-[c:18]2[s:19][cH:20][cH:21][n:22]2)[c:9]2[n:10][c:11]([N:34]3[CH2:33][CH:32]([NH:31][CH2:30][C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:29])[CH:36]([O:37][CH3:38])[CH2:35]3)[cH:12][cH:13][c:14]2[c:15]1=[O:16]

参加物

反応物 2

HCID 18969071Tert-butyl 2-[(4-methoxypyrrolidin-3-yl)amino]acetate

HCID 46928270Ethyl 7-chloro-4-oxo-1-(thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate

生成物 1

HCID 70201586Ethyl 7-[3-methoxy-4-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]pyrrolidin-1-yl]-4-oxo-1-(1,3-thiazol-2-yl)-1,8-naphthyridine-3-carboxylate

出典と根拠

ORDレコード: ord-c10ddcff4122446583e2f1a18e02b324
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…