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Phenylboronic Acid → 4-(5-Phenylpyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenylboronic Acid | HCID 66827 | — |
| 反応物 | 4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane | HCID 86649249 | — |
| 生成物 | 4-(5-Phenylpyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane | HCID 49869430 | — |
反応手順
The title compound was prepared from the product of Example 65A and phenylboronic acid according to General Method B: 1H NMR (500 MHz, CDCl3) δ ppm 6 ppm 8.14 (d, 2 H), 7.56 (d, 2 H), 7.46 (t, 2 H), 7.39 (t, 1 H), 7.10 (s, 1 H), 3.73-3.37 (m, 5 H), 3.05-2.97 (m, 3 H), 2.27-2.17 (m, 4 H), 1.88-1.77 (m, 3 H); LC-MS Method D (ESI+) m/z 306.0 (M+H)+, retention time 1.28 minutes.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08846661B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-599af1c2b56545d7a37f30bc44d1b743 |
| 出典メモ | uspto-grants-2014_09 |