3-Tolylboronic acid → 4-[5-(3-Methylphenyl)-1,3-thiazol-2-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane
反応式
Br[C:2]1[S:6][C:5]([N:7]2[CH2:15][CH:14]3[CH2:16][N:10]4[CH2:11][CH:12]([CH2:17][CH:8]2[CH2:9]4)[CH2:13]3)=[N:4][CH:3]=1.[CH3:18][C:19]1[CH:20]=[C:21](B(O)O)[CH:22]=[CH:23][CH:24]=1>>[CH3:18][C:19]1[CH:24]=[C:23]([C:2]2[S:6][C:5]([N:7]3[CH2:15][CH:14]4[CH2:16][N:10]5[CH2:11][CH:12]([CH2:17][CH:8]3[CH2:9]5)[CH2:13]4)=[N:4][CH:3]=2)[CH:22]=[CH:21][CH:20]=1参加物
3
実験手順
The title compound was prepared from the product of Example 105A and 3-methylphenylboronic acid according to General Method C: LC-MS Method D (ESI+) m/z 326.0 (M+H)+, retention time 1.55 minutes.
出典と根拠
- ORDレコード
- ord-e8950d907a834e44947f5c07e3d447f8
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08846661B2
反応ノート
読み込み中…