関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | 2-Acetamido-6-methylbenzoic acid | HCID 2801400 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 6-Acetylamino-2-methyl-3-nitro-benzoic acid | HCID 15283171 | — |
反応手順
271 ml of 98% nitric acid are initially taken at -5° C. and 106 g (0.55 mol) of the 2-methyl-6-acetamidobenzoic acid prepared in 1. are added in portions. After stirring at 10° C. for one hour, the reaction mixture is poured into a mixture of 540 g of ice and 270 ml of water. The deposited precipitate is filtered off with suction, washed with water and dried under reduced pressure at 50° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05723415 |
|---|
| 出典データセット | uspto-grants-1998_03 |
|---|
| ORD ID | ord-036dc1bd98f447088e22557193b51876 |
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| 出典メモ | uspto-grants-1998_03 |
|---|
