Methanol → Tert-butyl 3-[(2,3-difluorophenyl)-hydroxymethyl]piperidine-1-carboxylate

反応式

[BH4-:24].[CH3:26][OH:27].[F:1][c:2]1[c:3]([C:4](=[O:5])[CH:6]2[CH2:7][N:8]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]2)[cH:19][cH:20][cH:21][c:22]1[F:23].[Na+:25]>>[F:1][c:2]1[c:3]([CH:4]([OH:5])[CH:6]2[CH2:7][N:8]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]2)[cH:19][cH:20][cH:21][c:22]1[F:23]