Dichloromethane → Methanesulfonic Acid

HRID 806410ノート

反応式

HRID 806410 の反応式
[CH3:1][C:2]1([C:5](=[O:6])[N:7]2[CH2:8][CH2:9][CH:10]([O:13][c:14]3[n:15][cH:16][c:17]([NH:24][C:25](=[O:26])[NH:27][c:28]4[n:29](-[c:37]5[cH:38][cH:39][c:40]([CH3:43])[cH:41][cH:42]5)[n:30][c:31]([C:33]5([CH3:36])[CH2:34][CH2:35]5)[cH:32]4)[c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]34)[CH2:11][CH2:12]2)[CH2:3][CH2:4]1.[CH3:44][S:45]([OH:46])(=[O:47])=[O:48].[Cl:49][CH2:50][Cl:51]>>[CH3:1][C:2]1([C:5](=[O:6])[N:7]2[CH2:8][CH2:9][CH:10]([O:13][c:14]3[n:15][cH:16][c:17]([NH:24][C:25](=[O:26])[NH:27][c:28]4[n:29](-[c:37]5[cH:38][cH:39][c:40]([CH3:43])[cH:41][cH:42]5)[n:30][c:31]([C:33]5([CH3:36])[CH2:34][CH2:35]5)[cH:32]4)[c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]34)[CH2:11][CH2:12]2)[CH2:3][CH2:4]1.[CH3:44][S:45](=[O:46])(=[O:47])[OH:48]

参加物

5

反応物 3

HCID 6344DichloromethaneHCID 6395Methanesulfonic AcidHCID 160614691-{1-[1-(1-Methyl-cyclopropanecarbonyl)-piperidin-4-yloxy] isoquinolin-4-yl}-3-[5-(1-methyl-cyclopropyl)-2-p-tolyl-2H-pyrazol-3-yl]-urea

生成物 2

HCID 6395Methanesulfonic AcidHCID 160614691-{1-[1-(1-Methyl-cyclopropanecarbonyl)-piperidin-4-yloxy] isoquinolin-4-yl}-3-[5-(1-methyl-cyclopropyl)-2-p-tolyl-2H-pyrazol-3-yl]-urea

出典と根拠

ORDレコード
ord-04294698842243fa9528f7c0ffc79b00
出典データセット
Test data from https://doi.org/10.1039/C8SC04228D

反応ノート

読み込み中…