(2-Isocyanatocyclopropyl)benzene → 4-[2-[4-amino-2-(ethoxymethyl)-6,7-dimethylimidazo[4,5-c]pyridin-1-yl]ethyl]-N-(2-phenylcyclopropyl)piperidine-1-carboxamide

反応式

[CH2:13]([CH3:14])[O:15][CH2:16][c:17]1[n:18]([CH2:29][CH2:30][CH:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[c:19]2[c:20]([c:21]([NH2:27])[n:22][c:23]([CH3:26])[c:24]2[CH3:25])[n:28]1.[c:1]1([CH:7]2[CH:8]([N:10]=[C:11]=[O:12])[CH2:9]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]2[CH:8]([NH:10][C:11](=[O:12])[N:34]3[CH2:33][CH2:32][CH:31]([CH2:30][CH2:29][n:18]4[c:17]([CH2:16][O:15][CH2:13][CH3:14])[n:28][c:20]5[c:19]4[c:24]([CH3:25])[c:23]([CH3:26])[n:22][c:21]5[NH2:27])[CH2:36][CH2:35]3)[CH2:9]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

参加物

反応物 2

HCID 582709(2-Isocyanatocyclopropyl)benzene

HCID 129729622-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine

生成物 1

HCID 223973734-[2-[4-amino-2-(ethoxymethyl)-6,7-dimethylimidazo[4,5-c]pyridin-1-yl]ethyl]-N-(2-phenylcyclopropyl)piperidine-1-carboxamide

出典と根拠

ORDレコード: ord-b8121b78b73448d2b0989d84e59c5488
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…