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HRID 80881作成日：2026年10月27日

1-[(1-Methylpiperidin-3-yl)methyl]piperazine → 3-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]-6-(4-trifluoromethylphenyl)pyridazine

https://huagongshe.com/reaction/80881

反応式

関与物質

役割名称HCID仕込み量
反応物1-[(1-Methylpiperidin-3-yl)methyl]piperazineHCID 2736940—
反応物Pyridazine, 3-chloro-6-[4-(trifluoromethyl)phenyl]-HCID 12449554—
生成物3-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]-6-(4-trifluoromethylphenyl)pyridazineHCID 15951317—

反応手順

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-trifluoromethylphenyl)pyridazine and (1-methylpiperidin-3-ylmethyl)piperazine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08846677B2
出典データセットuspto-grants-2014_09
ORD IDord-fa2c8ae6bd9046c998b5515af50314ae
出典メモuspto-grants-2014_09