関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | L-Tryptophan | HCID 6305 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 生成物 | Tryptophan butyl ester | HCID 11666077 | 181.9% |
反応手順
L-Tryptophane (5 g; 24.5 mmol) and thionyl chloride (73.5 mmol; 5.3 ml) were dissolved in n-butanol (80 ml) and stirred at 100° C. over night. The product 5 precipitated after cooling to room temperature, was filtered off and washed with ice cold butanol and petrol ether. The product was dried at the oil pump, yielding 5.8 g of 5 (91%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08846682B2 |
|---|
| 出典データセット | uspto-grants-2014_09 |
|---|
| ORD ID | ord-4ed8fe63fe6941eca33ae882bbf034d6 |
|---|
| 出典メモ | uspto-grants-2014_09 |
|---|
