関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Nitroethane | HCID 6587 | — |
| 反応物 | Ammonium Acetate | HCID 517165 | — |
| 反応物 | 6-fluoro-5-methoxy-1H-indole-3-carbaldehyde | HCID 22014804 | — |
| 生成物 | 6-fluoro-5-methoxy-3-(2-nitro-propenyl)-1H-indole | HCID 69516792 | 92% |
反応手順
A mixture of nitroethane(44 ml, 611 mmol), 6-fluoro-5-methoxy-1H-indole-3-carbaldehyde (11.8 g, 61 mmol), and ammonium acetate(1.78 g, 23 mmol) is stirred at 100° C. for 3 hours, allowed to cool, and is filtered to give 14 g of 6-fluoro-5-methoxy-3-(2-nitro-propenyl)-1H-indole (92%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07087635B2 |
|---|
| 出典データセット | uspto-grants-2006_08 |
|---|
| ORD ID | ord-a2dc7544472245ceae1897b7f180e6d7 |
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| 出典メモ | uspto-grants-2006_08 |
|---|
