Acetone → (3aRS,4RS,6SR,7aSR)-6-bromomethyl-4-(2-methoxyphenyl)-2-[(2-methoxyphenyl)acetyl]perhydroisoindol-4-ol

反応式

[Br-:42].[CH3:1][O:2][c:3]1[c:4]([C:9]2([OH:40])[CH:10]3[CH2:11][N:12]([C:29]([CH2:30][c:31]4[c:32]([O:37][CH3:38])[cH:33][cH:34][cH:35][cH:36]4)=[O:39])[CH2:13][CH:14]3[CH2:15][CH:16]([CH2:18][S:19]([c:20]3[cH:21][cH:22][c:23]([CH3:24])[cH:25][cH:26]3)(=[O:27])=[O:28])[CH2:17]2)[cH:5][cH:6][cH:7][cH:8]1.[CH3:43][C:44](=[O:45])[CH3:46].[Li+:41]>>[CH3:1][O:2][c:3]1[c:4]([C:9]2([OH:40])[CH:10]3[CH2:11][N:12]([C:29]([CH2:30][c:31]4[c:32]([O:37][CH3:38])[cH:33][cH:34][cH:35][cH:36]4)=[O:39])[CH2:13][CH:14]3[CH2:15][CH:16]([CH2:18][Br:42])[CH2:17]2)[cH:5][cH:6][cH:7][cH:8]1