Acetate → 2-[2-[1-(2-Methyl-pyrimidin-4-yl)-piperidin-4-ylamino]-6-(4-trifluoromethyl-phenyl)-pyrimidin-4-yl]-propan-2-ol
反応式
[C:26](=[O:27])([O-:28])[O-:29].[CH3:34][c:35]1[n:36][cH:37][cH:38][c:39]([N:41]2[CH2:42][CH2:43][CH:44]([NH2:47])[CH2:45][CH2:46]2)[n:40]1.[CH:1]1([P:2]([CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1.[Cl:48][c:49]1[n:50][c:51](-[c:59]2[cH:60][cH:61][c:62]([C:65]([F:66])([F:67])[F:68])[cH:63][cH:64]2)[cH:52][c:53]([C:55]([CH3:56])([CH3:57])[OH:58])[n:54]1.[ClH:32].[ClH:33].[K+:30].[K+:31].[O-:77][C:78]([CH3:79])=[O:80].[O-:81][C:82]([CH3:83])=[O:84].[O:69]1[CH2:70][CH2:71][O:72][CH2:73][CH2:74]1.[OH2:75].[Pd+2:76]>>[CH3:34][c:35]1[n:36][cH:37][cH:38][c:39]([N:41]2[CH2:42][CH2:43][CH:44]([NH:47][c:49]3[n:50][c:51](-[c:59]4[cH:60][cH:61][c:62]([C:65]([F:66])([F:67])[F:68])[cH:63][cH:64]4)[cH:52][c:53]([C:55]([CH3:56])([CH3:57])[OH:58])[n:54]3)[CH2:45][CH2:46]2)[n:40]1
