化工社化工社 化学情報印刷レポート · 研究参考用
Water → 5-Bromo-3,4-dihydroxybenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 3,4-Dihydroxybenzaldehyde | HCID 8768 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 5-Bromo-3,4-dihydroxybenzaldehyde | HCID 85405 | 48% |
反応手順
To a solution of 3,4-dihydroxy benzaldehyde (15.48 g, 112 mmol) in 500 ml AcOH was added bromine (6.1 ml, 118 mmol) drop-wise in 50 ml AcOH over 10 min. After 4 h the mixture was poured into cold H2O. The precipitate was filtered, washed with cold H2O and dried in vacuum to give 3-bromo-4,5-dihydroxy-benzaldehyde (11.64 g, 48%) as a grey solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08846705B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-2a2d7a032d404c9d80a6dad6c2b94dbf |
| 出典メモ | uspto-grants-2014_09 |