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1-Benzyloxy-4-phenyl-butan-2-ol → 1-Benzyloxy-4-phenyl-butan-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Benzyloxy-4-phenyl-butan-2-ol | HCID 13347371 | — |
| 反応物 | HCID 178418287 | HCID 178418287 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-Benzyloxy-4-phenyl-butan-2-one | HCID 21992782 | 68.3% |
反応手順
To a solution of 1-benzyloxy-4-phenyl-butan-2-ol, (8.4 g, 32.8 mmol) in dichloromethane (400 mL) is added a mixture of pyridinium chlorochromate (14.1 g, 65.6 mmol) with SiO2 (14 g) and stirred for 3 h at room temperature. The mixture is filtered through a pad of SiO2 and concentrated to provide the title compound 5.7 g (68%) as a colorless liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07087626B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-16f69d03a0444212bf99c7b0fcc0694b |
| 出典メモ | uspto-grants-2006_08 |