Methanol → 4,4-Dimethyl-1-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline

HRID 819656ノート

反応式

[BH4-:23].[CH3:1][C:2]1([CH3:22])[CH2:3][N:4]=[C:5]([c:12]2[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21.[CH3:25][OH:26].[Na+:24]>>[CH3:1][C:2]1([CH3:22])[CH2:3][NH:4][CH:5]([c:12]2[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21