N,N-Dimethylpropargylamine → 4-(2,4-Dichloroanilino)-7-[3-(dimethylamino)prop-1-ynyl]quinoline-3-carbonitrile

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:14][c:15]3[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]3)[c:7]([C:12]#[N:13])[cH:8][n:9][c:10]2[cH:11]1.[CH3:23][N:24]([CH2:25][C:26]#[CH:27])[CH3:28]>>[c:2]1([C:27]#[C:26][CH2:25][N:24]([CH3:23])[CH3:28])[cH:3][cH:4][c:5]2[c:6]([NH:14][c:15]3[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]3)[c:7]([C:12]#[N:13])[cH:8][n:9][c:10]2[cH:11]1

参加物

反応物 2

HCID 81643N,N-Dimethylpropargylamine

HCID 234381007-Bromo-4-(2,4-dichloro-phenylamino)-quinoline-3-carbonitrile

生成物 1

HCID 102222954-(2,4-Dichloroanilino)-7-[3-(dimethylamino)prop-1-ynyl]quinoline-3-carbonitrile

出典と根拠

ORDレコード: ord-f7768f45712344ac841f1133eaeed45f
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…