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1-Phenylcyclopropanecarboxylic acid → N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}-1-phenylcyclopropanecarboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Phenylcyclopropanecarboxylic acid | HCID 80206 | — |
| 反応物 | (5-aminopyridin-3-yl)(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone | HCID 70817432 | — |
| 生成物 | N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}-1-phenylcyclopropanecarboxamide | HCID 70817501 | — |
反応手順
The title compound was prepared according to the method described for Library protocol 1 starting from (5-amino-pyridin-3-yl)-(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone (Preparation 110) and 1-phenylcyclopropanecarboxylic acid to afford the title compound. LCMS: Rt=2.61 min; m/z 398 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08846698B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-1a0851c861bf4327bd87333031dcb91a |
| 出典メモ | uspto-grants-2014_09 |