4-Bromopyrazole → tert-Butyl 2-(4-bromo-1H-pyrazol-1-yl)acetate

反応式

[Br:1][C:2]1[CH:3]=[N:4][NH:5][CH:6]=1.Br[CH2:8][C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10]>>[C:12]([O:11][C:9](=[O:10])[CH2:8][N:4]1[CH:3]=[C:2]([Br:1])[CH:6]=[N:5]1)([CH3:15])([CH3:14])[CH3:13]

参加物

反応物 2

HCID 163754-Bromopyrazole

HCID 79177tert-Butyl bromoacetate

生成物 1

HCID 70847699tert-Butyl 2-(4-bromo-1H-pyrazol-1-yl)acetate

実験手順

The title compound was prepared according to the method described for Preparation 79 using 4-bromo-1H-pyrazole and tert butyl bromoacetate to afford the title compound as a yellow solid in 34% yield, 48.0 g.

後処理

customThe title compound was prepared

出典と根拠

ORDレコード: ord-f544ae30f3f544d4a27e8809186ee9bc
出典データセット: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08846698B2

反応ノート

読み込み中…