2-(Oxan-2-yloxy)-2-phenylacetic acid → HCID 70817713、化合物
反応式
[C:1]1([CH:7]([O:11][CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][O:13]2)[C:8]([OH:10])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:18][C:19]1[CH:20]=[C:21]([C:25]([C:27]2[C:35]3[CH:34]=[N:33][CH:32]=[N:31][C:30]=3[N:29]([CH:36]([CH3:38])[CH3:37])[CH:28]=2)=[O:26])[CH:22]=[N:23][CH:24]=1>>[CH:36]([N:29]1[C:30]2[N:31]=[CH:32][N:33]=[CH:34][C:35]=2[C:27]([C:25]([C:21]2[CH:20]=[C:19]([NH:18][C:8](=[O:10])[CH:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[O:11][CH:12]3[CH2:17][CH2:16][CH2:15][CH2:14][O:13]3)[CH:24]=[N:23][CH:22]=2)=[O:26])=[CH:28]1)([CH3:38])[CH3:37]参加物
3
実験手順
The title compound was prepared according to the method described for Example 1 using phenyl-[(tetrahydro-pyran-2-yloxy)]-acetic acid (Preparation 236) and (5-Amino-pyridin-3-yl)-(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone (Preparation 95) to afford the title compound as a yellow solid in 68% yield, 60 mg.
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-6cb195ca1b1c415b8ffce649bc12bcec