4-(Methanesulfonyl)phenylboronic acid → 2-(4'-Methanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]([CH3:20])[c:11]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[n:12]2)[cH:6][cH:7]1.[CH3:21][S:22](=[O:23])(=[O:24])[c:25]1[cH:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][cH:30]1>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([S:22]([CH3:21])(=[O:23])=[O:24])[cH:30][cH:29]2)[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]([CH3:20])[c:11]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[n:12]2)[cH:6][cH:7]1

参加物

反応物 2

HCID 27343644-(Methanesulfonyl)phenylboronic acid

HCID 116815462-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

生成物 1

HCID 115605942-(4'-Methanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

出典と根拠

ORDレコード: ord-3a9edb95309c46d0b9b4da2484587d48
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…