Hydrochloric Acid → HCID 178478314、化合物

HRID 82566

反応式

HRID 82566 の反応式
CS[C:3]1[NH:11][C:6]2=[N:7][CH:8]=[CH:9][CH:10]=[C:5]2[N:4]=1.[ClH:12]>>[Cl:12][C:3]1[NH:11][C:6]2=[N:7][CH:8]=[CH:9][CH:10]=[C:5]2[N:4]=1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 178503348HCID 178503348、化合物

生成物 1

HCID 178478314HCID 178478314、化合物

反応条件

温度
0 °C

実験手順

2-(Methylthio)-3H-imidazo[4,5-b]pyridine (3.5 g) was dissolved in conc. HCl (10 mL), and then the mixture was cooled to 0° C. Chlorine gas was bubbled through the mixture for 2 h in iced bath. The mixture was poured onto ice, and neutralized to pH 7 with aqueous ammonium solution. The precipitate was collected by filtration to give the title compound as white crystals (1.0 g).

後処理

  1. customChlorine gas was bubbled through the mixture for 2 h in iced bath
  2. additionThe mixture was poured onto ice
  3. filtrationThe precipitate was collected by filtration

出典と根拠

ORDレコード
ord-0d86605a2fca46b7baa041ea345da716
出典データセット
uspto-grants-2014_09
特許番号
US08846713B2

関連ノート

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