3,4-Diaminopyridine → HCID 178527813、化合物

HRID 82614

反応式

HRID 82614 の反応式
[N:1]1[CH:6]=[CH:5][C:4]([NH2:7])=[C:3]([NH2:8])[CH:2]=1.[C:9](=S)=[S:10].[Cl-].[Cl-].[Ca+2]>CCO>[NH:7]1[C:4]2[CH:5]=[CH:6][N:1]=[CH:2][C:3]=2[N:8]=[C:9]1[SH:10]

参加物

5

反応物 3

HCID 59183,4-DiaminopyridineHCID 6348Carbon DisulfideHCID 5284359Calcium Chloride

生成物 1

HCID 178527813HCID 178527813、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To a solution of pyridine-3,4-diamine (5 g) in EtOH (80 mL) was added carbon disulfide (10 mL) at room temperature. The mixture was stirred at 40° C. under a dry atmosphere (CaCl2 tube) for 10 h. The mixture was cooled to room temperature. The resulting white solid was collected by filtration and washed with ether to give 1H-imidazo[4,5-c]pyridine-2-thiol (6.1 g) as a white solid.

後処理

  1. filtrationThe resulting white solid was collected by filtration
  2. washwashed with ether

出典と根拠

ORDレコード
ord-88ede3cd1b83468fa729786abb80d652
出典データセット
uspto-grants-2014_09
特許番号
US08846713B2

関連ノート

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