2-Amino-5-iodopyrimidine → 3-(2-Amino-pyrimidin-5-ylethynyl)-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine-8-carbonitrile

反応式

[C:1](#[CH:2])[c:3]1[cH:4][n:5][c:6]2[n:7]1[cH:8][c:9](-[c:14]1[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1)[cH:10][c:11]2[C:12]#[N:13].[NH2:24][c:25]1[n:26][cH:27][c:28]([I:31])[cH:29][n:30]1>>[C:1](#[C:2][c:28]1[cH:27][n:26][c:25]([NH2:24])[n:30][cH:29]1)[c:3]1[cH:4][n:5][c:6]2[n:7]1[cH:8][c:9](-[c:14]1[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1)[cH:10][c:11]2[C:12]#[N:13]

参加物

反応物 2

HCID 2411022-Amino-5-iodopyrimidine

HCID 866080963-Ethynyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine-8-carbonitrile

生成物 1

HCID 167382703-(2-Amino-pyrimidin-5-ylethynyl)-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine-8-carbonitrile

出典と根拠

ORDレコード: ord-0cdf414edde34a15b35a8c6747d970d1
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…