Bromine → 2-Amino-5-bromonicotinaldehyde hydrobromide
反応式
[Br:1]Br.[NH2:3][C:4]1[C:9]([CH:10]=[O:11])=[CH:8][CH:7]=[CH:6][N:5]=1>C(O)(=O)C>[BrH:1].[NH2:3][C:4]1[N:5]=[CH:6][C:7]([Br:1])=[CH:8][C:9]=1[CH:10]=[O:11]参加物
4
実験手順
A solution of bromine (1.05 mL, 20.0 mmol) in acetic acid (20 mL) was added to a solution of 2-amino-3-pyridinecarboxaldehyde (2.5 g, 20 mmol) in acetic acid (50 mL) at room temperature. The reaction mixture was then stirred overnight. The resulting precipitate was filtered and washed with diethyl ether to give the title compound as a white solid (4.66 g, 80%).
後処理
- filtrationThe resulting precipitate was filtered
- washwashed with diethyl ether
出典と根拠
- ORDレコード
- ord-1e3510f160a743ec895def1e08a146d2
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08846711B2
反応ノート
読み込み中…