化工社化工社 化学情報印刷レポート · 研究参考用
Hydroxyamine hydrochloride → 17beta-Acetoxy-2,3-dihydroxyimino-5alpha-androstane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | Acetic acid, sodium salt, monohydrate | HCID 23681166 | — |
| 反応物 | 2-Hydroxyimino-17beta-hydroxy-5alpha-androstan-3-one | HCID 86752163 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 17beta-Acetoxy-2,3-dihydroxyimino-5alpha-androstane | HCID 136395990 | — |
反応手順
A suspension of steroid 7, NH2OH.HCl and NaOAc/H2O was refluxed for 20 minutes. The reaction was cooled to room temperature and poured into H2O. The precipitate was collected by filtration. The resulting solid 8 was washed with H2O and air and dried; wt. 23.4 g.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05723455 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-4fe7e7b0295444c08046dd75241f89c9 |
| 出典メモ | uspto-grants-1998_03 |