Dichloromethane → Methyl 2'-fluoro-2-(2-methyl-5-((methylsulfonyl)oxy)cyclopentyl)-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate

反応式

[CH3:27][S:28]([Cl:29])(=[O:30])=[O:31].[Cl:32][CH2:33][Cl:34].[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH:20]3[CH:21]([OH:26])[CH2:22][CH2:23][CH:24]3[CH3:25])[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH:20]3[CH:21]([O:26][S:28]([CH3:27])(=[O:30])=[O:31])[CH2:22][CH2:23][CH:24]3[CH3:25])[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1

参加物

反応物 3

HCID 6344Dichloromethane

HCID 31297Methanesulfonyl chloride

HCID 57705852Methyl 2'-fluoro-2-(2-hydroxy-5-methylcyclopentyl)-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate

生成物 1

HCID 57707123Methyl 2'-fluoro-2-(2-methyl-5-((methylsulfonyl)oxy)cyclopentyl)-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate

出典と根拠

ORDレコード: ord-fb6a42225e154245a52a79031ca45332
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…