Acetate → Methyl 2-[(8-benzyl-6-cyano-1-phenyl-8-azabicyclo[3.2.1]octan-2-yl)oxy]-2-[3,5-bis(trifluoromethyl)phenyl]acetate

反応式

[C:52]([O-:53])(=[O:54])[CH3:55].[C:57]([O-:58])(=[O:59])[CH3:60].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH:10]([OH:18])[CH2:11][CH2:12][CH:13]1[CH:14]([C:16]#[N:17])[CH2:15]2.[N+:25](=[N-:26])=[C:27]([C:28](=[O:29])[O:30][CH3:31])[c:32]1[cH:33][c:34]([C:42]([F:43])([F:44])[F:45])[cH:35][c:36]([C:38]([F:39])([F:40])[F:41])[cH:37]1.[Rh+2:56].[cH:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH:10]([O:18][CH:27]([C:28](=[O:29])[O:30][CH3:31])[c:32]3[cH:33][c:34]([C:42]([F:43])([F:44])[F:45])[cH:35][c:36]([C:38]([F:39])([F:40])[F:41])[cH:37]3)[CH2:11][CH2:12][CH:13]1[CH:14]([C:16]#[N:17])[CH2:15]2