関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Ethyl 2-bromopropionate | HCID 79040 | — |
| 反応物 | Bis-alpha-naphthyl-(2,4-dihydroxyphenyl)-triazine | HCID 136338648 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Bis-alpha-naphthyl-(4-[1-ethoxycarbonyl-ethoxy]-2-hydroxy-phenyl)-triazine | HCID 136338649 | — |
反応手順
9.39 g of potassium carbonate and 9.02 g of 2-bromopropionic acid ethyl ester are added to a solution of 20.0 g of the product from Example A6 in 200 ml of DMF. The reaction mixture is heated at 125° C. for 3.5 h. The solid which precipitates is filtered off and washed with toluene. The combined organic phase is freed of solvent in vac. Chromatography of the residue on silica gel yields the product of melting point: 124–125° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07087753B2 |
|---|
| 出典データセット | uspto-grants-2006_08 |
|---|
| ORD ID | ord-692c51953fd446438dbb2938ec9d651f |
|---|
| 出典メモ | uspto-grants-2006_08 |
|---|
