Dimethylformamide → t-Butyl 5-(6-hydroxymethylpyridin-2-yl)pent-4-ynoate

HRID 836336

反応式

[Br:1][c:2]1[n:3][c:4]([CH2:8][OH:9])[cH:5][cH:6][cH:7]1.[C:10]([CH2:11][CH2:12][C:13]#[CH:14])(=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20].[C:21]([NH2:22])([CH3:23])([CH3:24])[CH3:25].[Cu:26][I:27].[O:105]=[CH:106][N:107]([CH3:108])[CH3:109].[cH:28]1[cH:29][cH:30][c:31]([P:32]([Pd:33]([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[cH:103][cH:104]1>>[c:2]1([C:14]#[C:13][CH2:12][CH2:11][C:10](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[n:3][c:4]([CH2:8][OH:9])[cH:5][cH:6][cH:7]1