Piperidine → 4-Piperidinylbut-1-ene

HRID 8380

反応式

HRID 8380 の反応式
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[NH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>>[N:6]1([CH2:7][CH2:8][CH:9]=[CH2:10])[CH2:11][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

3

反応物 2

HCID 8082PiperidineHCID 21241Homoallyl bromide

生成物 1

HCID 45622824-Piperidinylbut-1-ene収率 93.4%

実験手順

4-Bromobut-1-ene (1.35 g) was treated with piperidine (1.7 g) and heated at reflux for 3 hours. The mixture was cooled to ambient temperature, filtered and the residue washed with ether (50 mL). The combined filtrate and washings were evaporated to give the title compound (1.3 g).

後処理

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with ether (50 mL)
  5. customThe combined filtrate and washings were evaporated

出典と根拠

ORDレコード
ord-d7ef957ab1cf46f68f1f4c42cdc7ceea
出典データセット
uspto-grants-2006_08
特許番号
US07087757B2

関連ノート

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