化工社化工社 化学情報印刷レポート · 研究参考用
Benzene → 5-Methyl(ethyl)-7-ethyl(methyl)pyrazolo[1,5-a]pyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzene | HCID 241 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2,4-Hexanedione | HCID 76355 | — |
| 反応物 | HCID 178418806 | HCID 178418806 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 5-Methyl(ethyl)-7-ethyl(methyl)pyrazolo[1,5-a]pyrimidine | HCID 70620675 | 87% |
反応手順
The compound was prepared, as described above, from 3-aminopyrazole (8.3 g) and hexane-2,4-dione (11.4 g) in ethanol with a catalytic amount of piperidine. The product was isolated as a colorless oil (14.0 g, 87% yield) via chromatography on basic alumina with benzene. Oil, b.p. 173°-177°/0.1mm. Mass spectrum M+ = 161.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04093617 |
| 出典データセット | uspto-grants-1978_06 |
| ORD ID | ord-d6204ff820794c7ca04b1d3f988a7fed |
| 出典メモ | uspto-grants-1978_06 |