Tert-Butylamine → HCID 20325511、化合物

HRID 838980ノート

反応式

HRID 838980 の反応式
[O:1]1[CH2:16][CH:2]1[CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[N:10][NH:11][C:12]2=[O:15])=[CH:7][CH:6]=1.[C:17]([NH2:21])([CH3:20])([CH3:19])[CH3:18]>>[C:17]([NH:21][CH2:16][CH:2]([OH:1])[CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[N:10][NH:11][C:12]2=[O:15])=[CH:7][CH:6]=1)([CH3:20])([CH3:19])[CH3:18]

参加物

3

反応物 2

HCID 6385Tert-ButylamineHCID 203254967-(2,3-Epoxypropoxy)-1(2H)-phthalazinone

生成物 1

HCID 20325511HCID 20325511、化合物

実験手順

7-(2,3-Epoxypropoxy)-1(2H)-phthalazinone was reacted with t-butylamine in a similar manner to that described in Example 1(iv) to give 7-(3-t-butylamino-2-hydroxypropoxy)-1(2H)-phthalazinone, the hydrochloride of which was recrystallised from ethanol and had m.p. 263°-264° (decomp).

出典と根拠

ORDレコード
ord-f7460ea83b9a407584fabeec8bf63be9
出典データセット
uspto-grants-1978_06
特許番号
US04093725

反応ノート

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