関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 1,3-Benzenediamine, N1,N1,N3,N3-tetramethyl- | HCID 89715 | — |
| 反応物 | 3,4,5,6-Tetrachloro-2-carboxy-4'-diethylaminobenzophenone | HCID 19956611 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Fthalide | HCID 33791 | 103% |
反応手順
A mixture of 2-(4-(diethylamino)benzoyl)-3,4,5,6-tetrachlorobenzoic acid (8.70 g.), N,N,N',N'-tetramethyl-m-phenylenediamine (3.61 g.) and acetic anhydride (5 ml.) was heated (to 90° C.). Addition of methanol (10 ml.) and slurrying the resulting product with methanol afforded 3-(2,4-bis(dimethylamino)phenyl)-3-(4-diethylamino)phenyl)-4,5,6,7-tetrachlorophthalide (I: X = (CH3)2N, Y2 = H, Y4 = (CH3CH2)2N, Z4 = Z5 = Z6 = Z7 = Cl) (5.60 g., m.p. 206°-207.5° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04094877 |
|---|
| 出典データセット | uspto-grants-1978_06 |
|---|
| ORD ID | ord-1a6a548937a94484a44172645606ae00 |
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| 出典メモ | uspto-grants-1978_06 |
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