化工社化工社 化学情報印刷レポート · 研究参考用
2-Pyrrolidone → 2-Chloro-10-(1-pyrrolin-2-YL)phenoxazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Pyrrolidone | HCID 12025 | — |
| 反応物 | Phosphorus oxychloride | HCID 24813 | — |
| 反応物 | 2-Chlorophenoxazine | HCID 10632580 | — |
| 生成物 | 2-Chloro-10-(1-pyrrolin-2-YL)phenoxazine | HCID 22754317 | — |
反応手順
Reaction of 2-chlorophenoxazine, 2-pyrrolidinone, and phosphorus oxychloride according to the procedure of Example 1 provides the free base 2-CHLORO-10-(1-PYRROLIN-2-YL)PHENOXAZINE as a distillable oil, b.p. 150°-165° C. at 0.1 mm Hg. Conversion of the free base to the hydrochloride salt affords 2-CHLORO-10-(1-PYRROLIN-2-YL)PHENOXAZINE HYDROCHLORIDE, m.p. 209.5°-213.5° C. (corr.), in a 40% overall yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04094981 |
| 出典データセット | uspto-grants-1978_06 |
| ORD ID | ord-33a7245c1104466aa64dcebe1f650e7f |
| 出典メモ | uspto-grants-1978_06 |