Phenylhydrazine → 2-phenylphthalazin-1(2h)-one

反応式

Br[CH:2](Br)[C:3]1[C:4]([C:9]([OH:11])=O)=[CH:5][CH:6]=[CH:7][CH:8]=1.[C:13]1([NH:19][NH2:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([N:19]2[N:20]=[CH:2][C:3]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[C:9]2=[O:11])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

反応物 2

HCID 7516Phenylhydrazine

HCID 3455532-(dibromomethyl)benzoic acid

生成物 1

HCID 2356262-phenylphthalazin-1(2h)-one収率 30.1%

実験手順

α,α-dibromo-o-toluic acid (29.4 g) and phenylhydrazine (34.6 g) were allowed to react as in Example 4. There was obtaoined 6.7 g (yield: 30%) of 2-phenyl-1-phthalazinone having a melting poin of 104°-105° C.

出典と根拠

ORDレコード: ord-08dba768ac024693b221cbd8dfac69ec
出典データセット: uspto-grants-1978_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04096143

反応ノート

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