Triethylamine → HCID 20322094、化合物

HRID 839814ノート

反応式

HRID 839814 の反応式
[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][NH2:6])[CH3:2].Br[CH2:11][CH:12]1[O:17][CH2:16][CH2:15][CH2:14][O:13]1.C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][NH:6][CH2:11][CH:12]1[O:17][CH2:16][CH2:15][CH2:14][O:13]1)[CH3:2]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 695242,2-DiethoxyethylamineHCID 3036832-Bromomethyl-1,3-dioxane

生成物 1

HCID 20322094HCID 20322094、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

2,2-Diethoxyethylamine (23.3 grams), 2-bromomethyl-1,3-dioxane (29.2 grams), triethylamine (25 ml) and toluene (150 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at reflux overnight. After this time the mixture is cooled and filtered. The filtrate is then distilled under reduced pressure to yield the desired product N-(2,2-diethoxyethyl)-N-(1,3-dioxan-2-ylmethyl)amine.

後処理

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction mixture is heated
  4. temperatureat reflux overnight
  5. temperatureAfter this time the mixture is cooled
  6. filtrationfiltered
  7. distillationThe filtrate is then distilled under reduced pressure

出典と根拠

ORDレコード
ord-ce262f535bd5422b949724e8ffee2c25
出典データセット
uspto-grants-1978_06
特許番号
US04097491

反応ノート

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