Triethylamine → HCID 20322099、化合物

HRID 839818ノート

反応式

HRID 839818 の反応式
[CH3:1][O:2][CH:3]([O:6][CH2:7][CH3:8])[CH2:4][NH2:5].Br[CH2:10][CH:11]1[O:16][CH2:15][CH2:14][CH2:13][O:12]1.C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:15][O:16][CH:11]([O:12][CH2:13][CH3:14])[CH2:10][NH:5][CH2:4][CH:3]1[O:2][CH2:1][CH2:8][CH2:7][O:6]1

参加物

5

反応物 3

HCID 8471TriethylamineHCID 3036832-Bromomethyl-1,3-dioxaneHCID 22766278HCID 22766278、化合物

生成物 1

HCID 20322099HCID 20322099、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

2-Methoxy-2-ethoxyethylamine (0.11 mole), 2-bromomethyl-1,3-dioxane (0.1 mole), triethylamine (20 ml) and toluene (150 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction is heated at reflux for a period of about 12 hours. After this time the reaction mixture is allowed to cool to room temperature and is filtered. The reaction mixture is then stripped of solvent and unreacted starting materials under reduced pressure to yield the desired product N-(2-methoxy-2-ethoxyethyl)-N-(1,3-dioxan-2-ylmethyl)amine.

後処理

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction is heated
  4. temperatureat reflux for a period of about 12 hours
  5. filtrationis filtered

出典と根拠

ORDレコード
ord-c9b116a5d4b644b2bf48d3fc72a38d25
出典データセット
uspto-grants-1978_06
特許番号
US04097491

反応ノート

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