化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Bromide → 3-Phenyl-5-(3-phenylpropyl)isoxazole-4-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | 3-Phenyl-5-(2-phenylethyl)isoxazole-4-carboxylic acid | HCID 23447906 | — |
| 生成物 | 3-Phenyl-5-(3-phenylpropyl)isoxazole-4-carboxylic acid | HCID 23447887 | 72% |
反応手順
The title compound was prepared as described for Compound 28A but substituting 2-phenylethylbromide for benzyl bromide. The crude was purified by flash chromatography (ethyl acetate-petroleum ether-acetic acid 1:1:0.01 mL) to afford the title compound (72%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06365591B1 |
| 出典データセット | uspto-grants-2002_04 |
| ORD ID | ord-5384ec8b06e24c5a8f96afdfd5615e71 |
| 出典メモ | uspto-grants-2002_04 |