Phenol → 1,1,1-Tribromo-2,2-bis(4-hydroxyphenyl)ethane

HRID 840335

反応式

HRID 840335 の反応式
S(=O)(=O)(O)O.[C:6]1([OH:12])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[Br:13][C:14]([Br:18])([Br:17])[CH:15]=O>O>[Br:13][C:14]([Br:18])([Br:17])[CH:15]([C:9]1[CH:10]=[CH:11][C:6]([OH:12])=[CH:7][CH:8]=1)[C:9]1[CH:10]=[CH:11][C:6]([OH:12])=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 996PhenolHCID 1118Sulfuric AcidHCID 8256Tribromoacetaldehyde

生成物 1

HCID 184210651,1,1-Tribromo-2,2-bis(4-hydroxyphenyl)ethane

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A 4-necked 3-L flask, is equipped with a mechanical stirrer, a nitrogen inlet, and thermometer, is charged with 83% sulfuric acid (640 g) and phenol (354 g). To the resulting milky mixture, tribromoacetaldehyde (380 g) in an additional funnel is added dropwise. The reaction temperature is maintained below 30° C. After the addition, the mixture is allowed to stir at the room temperature for 18 hours, before water (640 g) is added. The resulting mixture is filtered and washed with more water to afford 1,1,1-tribromo-2,2-bis(4-hydroxyphenyl)ethane.

後処理

  1. customA 4-necked 3-L flask, is equipped with a mechanical stirrer, a nitrogen inlet
  2. temperatureThe reaction temperature is maintained below 30° C
  3. additionAfter the addition
  4. additionis added
  5. filtrationThe resulting mixture is filtered
  6. washwashed with more water

出典と根拠

ORDレコード
ord-32a1ed7043b04dc68d88530aff7f30ea
出典データセット
uspto-grants-2002_04
特許番号
US06365671B1

関連ノート

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