2,6-Dimethyl-4-pyranone → 2,6-Dimethyloxan-4-ol

HRID 840391

反応式

HRID 840391 の反応式
[CH3:1][C:2]1[O:3][C:4]([CH3:9])=[CH:5][C:6](=[O:8])[CH:7]=1.[H][H]>C(O)C>[CH3:1][CH:2]1[CH2:7][CH:6]([OH:8])[CH2:5][CH:4]([CH3:9])[O:3]1

参加物

4

反応物 2

HCID 138622,6-Dimethyl-4-pyranoneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 151823572,6-Dimethyloxan-4-ol収率 74%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

2,6-Dimethyl-4H-pyran-4-one (5.0 g) in ethanol (40 ml) was hydrogenated under 10% Pd—C (0.5 g) at 10 bar of hydrogen for 2 days. The solution was then evaporated to an oil which was purified by silica-gel MPLC [using a 1:1 mixture of ethyl acetate and hexane as eluant] to give the title product (3.71 g, 74%).

後処理

  1. customThe solution was then evaporated to an oil which
  2. customwas purified by silica-gel MPLC [
  3. additiona 1:1 mixture of ethyl acetate and hexane as eluant]

出典と根拠

ORDレコード
ord-24bf56278c174f3181d06e5553761ff1
出典データセット
uspto-grants-2002_04
特許番号
US06365751B1

関連ノート

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