Hydrochloric Acid → HCID 22617787、化合物

HRID 842073ノート

反応式

HRID 842073 の反応式
[CH2:1]([N:8]([CH2:29][CH3:30])[C:9](=[O:28])[CH2:10][N:11]1[C:19](=[O:20])[N:18]([CH3:21])[C:17]2[C:12]1=[N:13][C:14]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[N:15][CH:16]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:31]>C(O)C>[ClH:31].[CH2:1]([N:8]([CH2:29][CH3:30])[C:9](=[O:28])[CH2:10][N:11]1[C:19](=[O:20])[N:18]([CH3:21])[C:17]2[C:12]1=[N:13][C:14]([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)=[N:15][CH:16]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 6433109Emapunil

生成物 1

HCID 22617787HCID 22617787、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

To a mixture of N-benzyl-N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-acetamide (0.8 g) obtained in Example 146 and ethanol (15 ml) is added 30% hydrochloric acid in ethanol (15 ml) at 80° C., and the mixture is stirred for 30 minutes. The reaction mixture is cooled to room temperature, and the precipitates are collected by filtration, and washed with ethanol to give the desired compound (0.85 g).

後処理

  1. filtrationthe precipitates are collected by filtration
  2. washwashed with ethanol

出典と根拠

ORDレコード
ord-88a8a3c6fdba4222a3d86421b74442b2
出典データセット
uspto-grants-2002_04
特許番号
US06372740B1

反応ノート

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