Diethyl methylmalonate → Diethyl 2-(2-(2-benzyloxyphenyl)ethyl)-2-methylmalonate

反応式

[CH3:1][CH2:2][O:3][C:4]([CH:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH3:7])=[O:5].[CH2:13]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28]I)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][C:6]([CH3:7])([C:4]([O:3][CH2:2][CH3:1])=[O:5])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

反応物 2

HCID 11857Diethyl methylmalonate

HCID 226187172-(2-Benzyloxyphenyl)ethyl iodide

生成物 1

HCID 22618873Diethyl 2-(2-(2-benzyloxyphenyl)ethyl)-2-methylmalonate

実験手順

2-Methylmalonic acid diethyl eater and 2-(2-benzyloxyphenyl)ethyl iodide were used in the same manner as working example 52 (S) to give the subject compound.

後処理

customto give the subject compound

出典と根拠

ORDレコード: ord-e20db442b6b2485e9a0f15ea1522f38d
出典データセット: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06372800B1

反応ノート

読み込み中…