Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

HRID 842283ノート

反応式

HRID 842283 の反応式
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

参加物

3

反応物 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772、化合物

生成物 1

HCID 226187412-Amino-2-ethyl-4-(4-octylphenyl)butanol

実験手順

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

後処理

  1. customobtained
  2. customhydrolysis in the same manner
  3. customto give the subject compound

出典と根拠

ORDレコード
ord-fc536b2b13004f55a41cb0148f2b6f51
出典データセット
uspto-grants-2002_04
特許番号
US06372800B1

反応ノート

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