Diethyl ethylmalonate → 2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

HRID 842284ノート

反応式

HRID 842284 の反応式
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH:15]([OH:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

参加物

3

反応物 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772、化合物

生成物 1

HCID 226187962-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

実験手順

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

後処理

  1. customobtained
  2. additionis treated in the same manners
  3. customto give the subject compound

出典と根拠

ORDレコード
ord-9daf5e9ccc0046e48fb74e6352479203
出典データセット
uspto-grants-2002_04
特許番号
US06372800B1

反応ノート

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